The battle over Zone-00 begins as Benten confronts his older brother Bishamon, the creator of the nightmare-inducing drug. With every creature, creation and witch on edge, who will emerge victorious and who will be forever changed by this war? Most importantly, what cruel fates will befall Ango Shima, the young master of the demon-slayers, and Saburo Kujo, the incarnation of the infamous red ogre, Kiyoami?