Average human teenage boy Tsukune accidentally enrolls at a boarding school for monsters—no, not jocks and popular kids, but bona fide werewolves, witches, and unnameables out of his wildest nightmares! On the plus side, all the girls have a monster crush on him. Especially far-from-average cute vampire Moka. On the O-negative side, she also has a burning, unquenchable thirst for his blood...

Now, can Tsukune and his unlikely group of friends and rivals save humanity from the evil members of monsterkind?